ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,097, issued on April 22, was assigned to BioSplice Therapeutics Inc. (San Diego).

"Isoquinolin-3-yl carboxamides and preparation and use thereof" was invented by Sunil Kumar KC (San Diego), Chi Ching Mak (San Diego), Brian Walter Eastman (San Diego), Jianguo Cao (San Diego), Venkataiah Bollu (San Diego), Gopi Kumar Mittapalli (San Diego) and Chandramouli Chiruta (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized b...