ALEXANDRIA, Va., March 12 -- United States Patent no. 12,246,098, issued on March 11, was assigned to BioPhysics Pharma Inc. (Gloucester, Mass.).
"Trans-epithelial membrane drug delivery system" was invented by John J. Masiz (Gloucester, Mass.) and Zhen Zhu (Andover, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to trans-epithelial membrane delivery systems, methods and kits that include an agent to penetrate the basement membrane, a membrane of the skin and mucosa previously known to be difficult to penetrate. In particular, the formulation includes a basement membrane disruptor that reversibly denatures or cleaves molecules of the basement membrane of the epithelial mem...