ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,422,428, issued on Sept. 23, was assigned to BIOMADISON INC. (Del Mar, Calif.).
"Compositions and methods for cell-based assays" was invented by Dhammika Atapattu (Madison, Wis.) and Ward C. Tucker (Monona, Wis.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for characterization binding proteins are described that include use of a reporting construct that incorporates a bait region that interacts with the binding protein and a reporter that is susceptible to degradation in the reporter's local environment. Complex formation between the bait region and the binding protein provides protection of the susceptible reporter from degr...