US Patent Issued to BIOMADISON on April 29 for "Reporting construct with synaptobrevin based moiety" (Wisconsin Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,287,323, issued on April 29, was assigned to BIOMADISON INC. (Del Mar, Calif.).

"Reporting construct with synaptobrevin based moiety" was invented by Timothy Piazza (McFarland, Wis.), Francis Mark Dunning (Madison, Wis.) and Ward C Tucker (Monona, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for improved cell-based methods of characterizing botulinum neurotoxins are provided. Cells utilized in these methods include a reporting construct that is cleaved following uptake and processing of botulinum neurotoxin by the cell, resulting in proteolysis of the portion of the reporting construct that is released following cleavage. ...