US Patent Issued to BIOINVENT INTERNATIONAL on May 6 for "Antibodies and nucleotide sequences, and uses thereof" (Swedish Inventors)

ALEXANDRIA, Va., June 10 -- United States Patent no. 12,291,569, issued on May 6, was assigned to BIOINVENT INTERNATIONAL AB (Lund, Sweden).

"Antibodies and nucleotide sequences, and uses thereof" was invented by Bjorn Frendeus (Lund, Sweden), Ingrid Teige (Lund, Sweden), Monika Semmrich (Malmo, Sweden), Linda Martensson (Bjarred, Sweden) and Petra Holmkvist (Kavlinge, Sweden).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described are novel anti-CTLA-4 antibody molecules and nucleotide sequences and expression vectors, such as viruses, encoding such antibody molecules. The novel antibody molecules are Treg depleting antibody molecules, and they have an improved depleting effect on CTLA-4 positive cells, suc...