ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,404,263, issued on Sept. 2, was assigned to BIOGEN MA INC. (Cambridge, Mass.).

"ASK1 inhibiting agents" was invented by Felix Gonzalez Lopez de Turiso (Cambridge, Mass.), Michael Dechantsreiter (Allston, Mass.), Zhili Xin (Cambridge, Mass.), John H. Jones (Framingham, Mass.) and Martin Himmelbauer (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are compounds of Formula (I):including compounds of Formulas (II), (III) and (IV), wherein X, R1, R2, R3 and n are as defined herein, and pharmaceutically acceptable salts thereof, and methods for their use and production. These compounds can be useful, e.g., in the treatment of disorder...