ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,467,929, issued on Nov. 11, was assigned to Biogen MA Inc. (Cambridge, Mass.).

"Methods of detecting UBE3A protein" was invented by Kyle Bradley Fraser (Cambridge, Mass.), Omar Sharif Mabrouk (Brookline, Mass.) and Danielle LeeZetta Graham (Concord, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a method of detecting the presence or amount of a UBE3A protein in a sample, such as a human sample, using mass spectrometry based techniques. The methods described herein are useful for diagnosing Angelman syndrome, as well as monitoring disease progression and treatment effectiveness."

The patent was filed on April 26, 20...