ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,360, issued on Nov. 18, was assigned to BioAtla Inc. (San Diego).
"Multi-specific antibody constructs" was invented by Jay M. Short (Del Mar, Calif.), Gerhard Frey (San Diego) and Hwai Wen Chang (San Marcos, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A multi-specific antibody contains at least one binding site for a cell specific antigen and at least one binding site for a tumor-reactive lymphocyte antigen and a multi-specific antibody including an IgG antibody or fragment thereof that binds to a first antigen; and at least one scFv antibody that binds to a second antigen that is different from the first antigen and is linked to a C termi...