ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,718, issued on Oct. 28, was assigned to Bio-Rad Laboratories Inc. (Hercules, Calif.).
"Digital analyte analysis" was invented by Jonathan William Larson (Chelsea, Mass.), Qun Zhong (Lexington, Mass.) and Darren Roy Link (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from ...