US Patent Issued to BicycleTx on Dec. 9 for "Bicyclic peptide ligands specific for PD-L1" (British, American Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,224, issued on Dec. 9, was assigned to BicycleTx Ltd. (Cambridge, Great Britain).

"Bicyclic peptide ligands specific for PD-L1" was invented by Liuhong Chen (Cambridge, Great Britain), James Cooke (Cambridge, Great Britain), Kevin McDonnell (Lexington, Mass.), Gemma Mudd (Cambridge, Great Britain), Katerine van Rietschoten (Cambridge, Great Britain) and Punit Upadhyaya (Lexington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to polypeptides which are covalently bound to non-aromatic molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the ...