ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,288, issued on Aug. 5, was assigned to BicycleTx Ltd. (Cambridge, Great Britain).
"Multimeric bicyclic peptide ligands" was invented by Liuhong Chen (Cambridge, Great Britain), Rachid Lani (Cambridge, Great Britain), Kevin McDonnell (Lexington, Mass.), Gemma Mudd (Cambridge, Great Britain), Peter U. Park (Lincoln, Mass.) and Punit Upadhyaya (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to multimers of polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. The invention also describes the multimerization...