ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,377,155, issued on Aug. 5, was assigned to BicycleRD Ltd. (Cambridge, Great Britain).
"Bicyclic peptide ligands specific for PSMA" was invented by Liuhong Chen (Cambridge, Great Britain), Catherine Stace (Cambridge, Great Britain), Daniel Teufel (Cambridge, Great Britain), Punit Upadhyaya (Lexington, Mass.) and Edward Walker (Cambridge, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity b...