US Patent Issued to BEIGENE SWITZERLAND on Feb. 25 for "Anti-TIGIT antibodies and their use as therapeutics and diagnostics" (Chinese Inventors)

ALEXANDRIA, Va., Feb. 26 -- United States Patent no. 12,234,286, issued on Feb. 25, was assigned to BEIGENE SWITZERLAND GMBH (Basel, Switzerland).

"Anti-TIGIT antibodies and their use as therapeutics and diagnostics" was invented by Tong Zhang (Beijing), Liu Xue (Beijing), Qi Liu (Beijing), Min Wei (Beijing) and Kang Li (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are antibodies that specifically bind to TIGIT (T cell immunoreceptor with Ig and ITIM domains, WUCAM or Vstm3) and inhibit Tigit-mediated cellular signaling and activities in immune cells. The anti-TIGIT antibodies can be used to treat or diagnose cancer, infectious diseases or other pathological disorders that may be modulated...