US Patent Issued to Becton Dickinson and Co. on Aug. 19 for "Single cell assay for transposase-accessible chromatin" (California Inventors)

ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,391,940, issued on Aug. 19, was assigned to Becton Dickinson and Co. (Franklin Lakes, N.J.).

"Single cell assay for transposase-accessible chromatin" was invented by Hye-Won Song (San Jose, Calif.) and Margaret Nakamoto (San Jose, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein include systems, methods, compositions, and kits for labeling DNA (e.g., open chromatin-associated gDNA). The method can comprise contacting double-stranded DNA (dsDNA), such as gDNA, with a transposome to generate a plurality of dsDNA fragments each comprising a first 5' overhang and a second 5' overhang. The transposome can comprise a transposase, a first...