ALEXANDRIA, Va., June 9 -- United States Patent no. 12,285,416, issued on April 29, was assigned to Battelle Memorial Institute (Columbus, Ohio).
"Compositions and methods for reducing muscle contraction" was invented by Brian L. Burback (Hilliard, Ohio), Jessica Catherine Bright (Dublin, Ohio) and Jerry D. Johnson (Dublin, Ohio).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods of reducing muscle contraction in a diaphragm or peripheral muscle(s) of a patient sufficient to permit a surgical procedure. The methods may comprise the step of administering an oxime or pharmaceutically acceptable salt thereof to a subject in need thereof in an amount sufficient to achieve said reduced mus...