ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,267, issued on March 25, was assigned to BASECLICK GMBH (Neuried, Germany).
"Click-modified mRNA" was invented by Thomas Frischmuth (Frischmuth, Germany), Sascha Serdjukow (Kiefersfelden, Germany), Birgit Graf (Munich) and Stefano Croce (Munich).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to alkyne- and/or azide-modified mRNA, processes for producing such modified mRNA, cells which are transfected to include the modified mRNA, pharmaceutical compositions containing the modified mRNA or cells including the modified mRNA, and to uses of such mRNA, cells or pharmaceutical compositions in mRNA based therapeutic and/or pr...