ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,533,346, issued on Jan. 27, was assigned to AXCESS GLOBAL SCIENCES LLC (Washington, Utah).

"Administration of berberine metabolites" was invented by Ryan Lowery (Tampa, Fla.), Jacob Wilson (Tampa, Fla.) and Shawn Wells (Lewisville, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "In various implementations, berberine metabolites, such as dihydroberberine and/or tetrahydroberberine, may be administered to manage blood glucose levels, increase ketone levels (e.g., blood concentration of ketones), and/or for therapeutic purposes in humans. The administration of a pharmaceutically effective amount of berberine metabolites, such as dihydroberberine, may ...