US Patent Issued to Avedro on July 1 for "Bis(diazirine) derivatives as photo-crosslinker for treating corneal ectatic disorders" (Massachusetts Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,598, issued on July 1, was assigned to Avedro Inc. (Waltham, Mass.).

"Bis(diazirine) derivatives as photo-crosslinker for treating corneal ectatic disorders" was invented by Jason Hill (Auburndale, Mass.) and Desmond Adler (Bedford, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure features bis(diazirine) derivatives of the formulae (I) (1-a) or (1-b) that generate cross-linking in the cornea in response to exposure to an electromagnetic irradiation (e.g. UV-light). The compounds are useful, e.g. for treating a subject (e.g. a human) having a disease, disorder or condition in which abnormal shaping of the cornea (e.g. thinning of t...