ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,255, issued on March 25, was assigned to AUSON PHARMACEUTICALS INC. (Bridgewater, N.J.).
"Timolol maleate gel for topical administration" was invented by Enxian Lu (East Brunswick, N.J.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A formulation for topical administration of timolol maleate is disclosed. The formulation, when administered at a daily dose from about 0.4 to about 15 mg/cm2/day, provides a steady state mean timolol blood Cmax,ss below 3 ng/ml in a subject in need thereof, wherein at steady state the ratio of Cmax,SS/Cmin,SS is less than 2. Also disclosed herein is a method of treating skin conditions such as infantile hemangiomas and...