US Patent Issued to Aurigene Oncology on May 6 for "Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors" (Indian Inventors)

ALEXANDRIA, Va., June 10 -- United States Patent no. 12,290,507, issued on May 6, was assigned to Aurigene Oncology Ltd. (Bangalore, India).

"Methods of use for trisubstituted benzotriazole derivatives as dihydroorotate oxygenase inhibitors" was invented by Kavitha Nellore (Bangalore, India) and Subramanya Hosahalli (Bangalore, India).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods for treating a cancer in a subject and for inhibiting tumor growth, metastasis or a dihydrorotate oxygenase enzyme activity of a tumor or cancer cell. At least one trisubstituted benzotriazole derivative with the formula (I) is administered to the subject or is contacted with the cancer cell. C...