ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,377,088, issued on Aug. 5, was assigned to AURIGENE ONCOLOGY Ltd. (Bangalore, India).

"Substituted tetrahydroquinolinone compounds as ROR gamma modulators" was invented by Ravi Kotrabasaiah Ujjinamatada (Anekal Taluk, India) and Chetan Pandit (Bangalore, India).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides substituted tetrahydroquinolinone and related compounds of formula (I), which are therapeutically useful as modulators of Retinoic acid receptor-related orphan receptors (RORs), more particularly as RORGamma modulators. These compounds are useful in the treatment and prevention of diseases and/or disorder, in particular t...