US Patent Issued to Atux Iskay on Jan. 13 for "2-diarylmethyl-4-aminotetrahydropyran derivatives and related compounds as anticancer, antiinflammatory, antifibrotic and neuroprotective agents" (New Jersey Inventor)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,575, issued on Jan. 13, was assigned to Atux Iskay LLC (Plainsboro, N.J.).

"2-diarylmethyl-4-aminotetrahydropyran derivatives and related compounds as anticancer, antiinflammatory, antifibrotic and neuroprotective agents" was invented by Michael Ohlmeyer (Plainsboro, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "2-diarylmethyl-4-aminotetrahydropyran derivatives are disclosed. The compounds include the following genus:or a pharmaceutically acceptable salt thereof.The compounds activate cellular PP2A, suppress oncogenic kinase signaling and negatively regulate MYC and MYCN in cancer. The compounds also induce FOXO transcription factor translocat...