ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,227,497, issued on Feb. 18, was assigned to ATEGRIN INC. (Miami).
"Solid forms of(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid" was invented by Antonio J. Barbosa (Ave Maria, Fla.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides new salts and crystalline forms of leukadherin LA1 [(Z)-4-(5-((3-benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid] according to Formula I. Methods for preparation of the salts and crystalline forms are also described, as well as methods for treating Beta2 integrin-mediated diseases and conditions using the salts and crystalline forms."...