ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,371, issued on Sept. 30, was assigned to ASYMCHEM LIFE SCIENCE (TIANJIN) Co. LTD (Tianjin, China).

"Preparation method for metformin hydrochloride" was invented by Hao Hong (Morrisville, N.C.), Jiangping Lu (Tianjin, China), Jian Tao (Tianjin, China), Yan Zhang (Tianjin, China), Fan Wang (Tianjin, China) and Gonzalez Miguel (Morrisville, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a preparation method for metformin hydrochloride. The preparation method includes: microwave heating raw materials containing dicyandiamide and dimethylamine hydrochloride, and reacting the two at 100deg C. to 160deg C. to obtain a ...