US Patent Issued to AstraZeneca on Oct. 7 for "Arginase inhibitors and methods of use thereof" (British, American Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,097, issued on Oct. 7, was assigned to AstraZeneca AB (Sodertalje, Sweden).

"Arginase inhibitors and methods of use thereof" was invented by Scott Nathan Mlynarski (Waltham, Mass.), Tyler Grebe (Waltham, Mass.), Sameer Kawatkar (Waltham, Mass.), Maurice Raymond Verschoyle Finlay (Cambridge, Great Britain) and Iain Simpson (Cambridge, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compounds of formula (Ib) or (Vc), or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of formula (Ib) or (Vc) and methods of using the same for treating cancer, respiratory inflammatory disease, and inh...