ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,744, issued on Oct. 14, was assigned to AstraZeneca AB.

"2,6,9-trisubstituted purines" was invented by Bernard Barlaam (Cambridge, Great Britain), Michael Bodnarchuk (Cambridge, Great Britain), Avipsa Ghosh (Waltham, Mass.), Frederick Goldberg (Cambridge, Great Britain), Sudhir Hande (Waltham, Mass.), Phillip Lichtor (Waltham, Mass.), Kun Song (Waltham, Mass.), Qibin Su (Waltham, Mass.), Reem Telmesani (Waltham, Mass.) and James Sheppeck (Waltham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds having the structure of Formula (I):and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, and R5 are as defined in the specif...