ALEXANDRIA, Va., June 12 -- United States Patent no. 12,296,026, issued on May 13, was assigned to Astellas Gene Therapies Inc. (South San Francisco, Calif.).
"Transcription regulatory elements and uses thereof" was invented by John T. Gray (San Francisco).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides regulatory elements, as well as vectors containing the same that may be used to stimulate transcription of a gene of interest in certain tissue types. The transcription regulatory elements described herein may be operably linked to a transgene, such as acid alpha-glucosidase (GAA), so as to promote expression of the GAA transgene in a cell, such as a muscle cell, liver cell, or neuron. Th...