ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,543, issued on Oct. 28, was assigned to Ascribe Bioscience Inc. (Ithaca, N.Y.).
"Process for production of ascarylose and related compounds" was invented by James Eagan (Ithaca, N.Y.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This application relates to efficient methods for the synthesis of ascarylose and its derivatives. A method for the production of ascarylose includes: providing, as a feedstock, a 1-O-substituted rhamnose; forming a mono-sulfonate ester at the 3-OH group of the 1-O-substituted rhamnose; and treating the mono-sulfonate ester with a hydride source to form a 1-O-substituted ascarylose. Forming the mono-sulfonate ester can adva...