ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,324, issued on Dec. 2, was assigned to Asclepius (Suzhou) Technology Co. Group Co. Ltd. (Suzhou, China).

"Chimeric antigen receptor cells targeting ROBO1, preparation method and use thereof" was invented by Huashun Li (Suzhou, China), Baolei Wang (Suzhou, China) and Kunkun Han (Suzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to chimeric antigen receptor cells targeting ROBO1, in particular, enhanced CAR-T cells and CAR-NK cells targeting ROBO1, and preparation and application thereof. The cells can stably expressing CAR elements, while secreting extracellular domain molecules expressing PD-1 protein or muta...