US Patent Issued to ASCENDIS PHARMA ONCOLOGY DIVISION on Sept. 30 for "Treating cancer with a conjugate comprising an IL-2 moiety" (Danish, American Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,461, issued on Sept. 30, was assigned to ASCENDIS PHARMA ONCOLOGY DIVISION A/S (Hellerup, Denmark).

"Treating cancer with a conjugate comprising an IL-2 moiety" was invented by Nina Gunnarsson (Hellerup, Denmark), Matiss Maleckis (Hellerup, Denmark) and David B. Rosen (Palo Alto, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an IL-2 protein sequence of the formula Ala-SEQ A-Cys*-SEQ B (I), wherein SEQ A has at least 94% sequence identity to SEQ ID NO:1; SEQ B has at least 94% sequence identity to SEQ ID NO:2; Ala is an alanine residue; and Cys* is a cysteine residue; to conjugates thereof and their uses in t...