US Patent Issued to Ascendis Pharma Endocrinology Division on April 15 for "PEGylated recombinant human growth hormone compounds" (German, Danish, Swiss Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,274,737, issued on April 15, was assigned to Ascendis Pharma Endocrinology Division A/S (Hellerup, Denmark).

"PEGylated recombinant human growth hormone compounds" was invented by Harald Rau (Dossenheim, Germany), Susanne Kindermann (Liestal, Switzerland), Torben LeBmann (Neustadt an der Weinstrasse, Germany), Grethe Norskov Rasmussen (Farum, Denmark), Ulrich Hersel (Heidelberg, Germany), Thomas Wegge (Heidelberg, Germany) and Kennett Sprogoe (Holte, Denmark).

According to the abstract* released by the U.S. Patent & Trademark Office: "A chemically modified human Growth Hormone (rhGH) prepared by attaching a transient linker which comprises a polyethylene glycol. The chemically modifie...