ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,399, issued on Oct. 21, was assigned to ARVINAS OPERATIONS INC. (New Haven, Conn.).
"Cereblon-based KRAS degrading PROTACs and uses related thereto" was invented by Jesus Raul Medina (Gilbertsville, Pa.) and Hanqing Dong (Madison, Conn.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds that target KRas and are thus useful in the treatment of cancer."
The patent was filed on Jan. 26, 2024, under Application No. 18/424,488.
*For further information, including images, charts and tables, please visit: http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1...