US Patent Issued to Arvinas Operations on Oct. 14 for "Cereblon ligands and bifunctional compounds comprising the same" (Connecticut, New Jersey Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,708, issued on Oct. 14, was assigned to Arvinas Operations Inc. (New Haven, Conn.).

"Cereblon ligands and bifunctional compounds comprising the same" was invented by Andrew P. Crew (Chester, Conn.), Michael Berlin (Flemington, N.J.), Keith R. Hornberger (Southbury, Conn.), Lawrence B. Snyder (Killingworth, Conn.), Jing Wang (Milford, Conn.), Yimin Qian (Plainsboro, N.J.), Hanqing Dong (Madison, Conn.) and Kurt Zimmermann (Durham, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The description relates to cereblon E3 ligase binding compounds, including bifunctional compounds comprising the same, which find utility as modulators of targeted ubiqui...