US Patent Issued to Arvinas Operations on May 27 for "Modulators of BCL6 proteolysis and associated methods of use" (Connecticut, New Jersey Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,310,975, issued on May 27, was assigned to Arvinas Operations Inc. (New Haven, Conn.).

"Modulators of BCL6 proteolysis and associated methods of use" was invented by Michael Berlin (Flemington, N.J.), Hanqing Dong (Madison, Conn.), Dan Sherman (Madison, Conn.), Lawrence Snyder (Killingworth, Conn.), Jing Wang (Milford, Conn.) and Wei Zhang (Madison, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Bifunctional compounds, which find utility as modulators of B-cell lymphoma 6 protein (BCL6; target protein), are described herein. In particular, the bifunctional compounds of the present disclosure contain on one end a Von Hippel-Lindau, cereblon, Inhibi...