ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,764, issued on Jan. 27, was assigned to Arog Pharmaceuticals Inc. (Plano, Texas).
"Crenolanib for treating FLT3 mutated proliferative disorders associated mutations" was invented by Vinay K. Jain (Dallas).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes methods for treating a FLT3 mutated proliferative disorder comprising: measuring expression of a mutated FLT3 and a one or more driver mutations in a nuclear transport protein that results in a loss of localization of the nuclear transport protein in a sample obtained from a tumor sample obtained from the patient, wherein the presence of the one or more genetic abnormaliti...