US Patent Issued to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY on July 1 for "Highly knotted molecular topologies from single-stranded nucleic acids" (Arizona Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,845, issued on July 1, was assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Ariz.).

"Highly knotted molecular topologies from single-stranded nucleic acids" was invented by Hao Yan (Chandler, Ariz.), Fei Zhang (Chandler, Ariz.) and Xiaodong Qi (Tempe, Ariz.).

According to the abstract* released by the U.S. Patent & Trademark Office: "In some embodiments, complex molecular knots with high crossing numbers are achieved by folding, following a prescribed folding order, single-stranded DNA or RNA of customized sequences into target shapes. Such complex molecular knots with high crossing numbers are useful for biomedical applications including use...