US Patent Issued to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY on Jan. 13 for "Loop-mediated synthetic riboregulators" (Arizona Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,878, issued on Jan. 13, was assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Ariz.).

"Loop-mediated synthetic riboregulators" was invented by Alexander Green (Scottsdale, Ariz.) and Duo Ma (Tempe, Ariz.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are synthetic nucleic acid molecules known as loop-mediated riboregulators that have single-nucleotide polymorphism (SNP) sensitivity and ultralow OFF state signal levels. Loop-mediated riboregulators can activate or repress gene expression in response to trigger RNAs bearing completely arbitrary sequences. Also provided herein are methods of using s...