US Patent Issued to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY on Dec. 30 for "DNA gridiron compositions and methods" (Massachusetts, Arizona Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,486, issued on Dec. 30, was assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Ariz.).

"DNA gridiron compositions and methods" was invented by Dongran Han (Cambridge, Mass.) and Hao Yan (Chandler, Ariz.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Novel compositions and methods for engineering wireframe architectures and scaffolds of increasing complexity by creating gridiron-like DNA structures (FIG. 1). A series of four-arm junctions are used as vertices within a network of double-helical DNA fragments. Deliberate distortion of the junctions from their most relaxed conformations ensures that a scaffold strand...