US Patent Issued to Arium BioLabs on June 10 for "Systems and methods for identifying positive allosteric modulators of enzymes to enhance activity" (Tennessee Inventor)

ALEXANDRIA, Va., June 18 -- United States Patent no. 12,326,454, issued on June 10, was assigned to Arium BioLabs LLC (Edmond, Okla.).

"Systems and methods for identifying positive allosteric modulators of enzymes to enhance activity" was invented by Pratul K. Agarwal (Knoxville, Tenn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and systems are provided for identifying positive allosteric modulators of proteins. Small compounds that enhance enzyme activity by binding to an allosteric site are identified, by analysis of biophysical and dynamics data for the target protein. More specifically, the present disclosure is directed to identifying and enhancing the dynamics and energetic behavior of dista...