ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,103, issued on April 22, was assigned to ARDELYX INC. (Fremont, Calif.).
"Compounds useful for treating gastrointestinal tract disorders" was invented by Dean Dragoli (Fremont, Calif.), Irina Dotsenko (Fremont, Calif.) and Jason Lewis (Fremont, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retenti...