ALEXANDRIA, Va., Dec. 2 -- United States Patent no. RE50,681, issued on Dec. 2, was assigned to Arcturus Therapeutics Inc (San Diego).
"Ionizable cationic lipid for RNA delivery" was invented by Joseph E. Payne (San Diego) and Padmanabh Chivukula (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "What is described is a compound of formula (1)wherein R1 and R2 are the same or different, each a linear or branched alkyl with 1-9 carbons, or an alkenyl or alkynyl with 2 to 11 carbon atoms; L1 and L2 are the same or different, each a linear alkyl having 5 to 18 carbon atoms, or form a heterocycle with N; X1 is a bond, or is -CO-O- whereby L2-CO-O-R2 is formed; X2 is S or O; L3 is a bond or a lower alkyl, o...