US Patent Issued to ARCTURUS THERAPEUTICS on Aug. 26 for "Compositions and methods for treating ornithine transcarbamylase deficiency" (California Inventors)

ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,379, issued on Aug. 26, was assigned to ARCTURUS THERAPEUTICS INC. (San Diego).

"Compositions and methods for treating ornithine transcarbamylase deficiency" was invented by Carlos G. Perez-Garcia (San Diego), Kiyoshi Tachikawa (San Diego), Daiki Matsuda (San Diego) and Padmanabh Chivukula (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a modified human OTC protein having improved properties for the treatment of OTC deficiency in a patient. Preferably, the protein of the disclosure is produced from a codon optimized mRNA suitable for administration to a patient suffering from OTC deficiency wherein upon admi...