US Patent Issued to Arcturus Therapeutics on April 29 for "Method of synthesis of an ionizable cationic lipid" (California Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,395, issued on April 29, was assigned to Arcturus Therapeutics Inc. (San Diego).

"Method of synthesis of an ionizable cationic lipid" was invented by Joseph E. Payne (San Diego) and Padmanabh Chivukula (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "What is described is a method of synthesis of the compound of formula 1A,or a salt thereof, wherein R3 is a linear or branched alkene of 1, 2, 3, 4, 5 or 6 carbons; R4 and R5 are the same or different, each a hydrogen, or a linear or branched alkyl of 1, 2, 3, 4, 5 or 6 carbons; and L3 is a bond or an alkane of 1, 2, 3, 4, 5 or 6 carbons."

The patent was filed on Sept. 21, 2020, under Applicati...