US Patent Issued to Arcellx, Subdomain on July 15 for "De novo binding domain containing polypeptides and uses thereof" (District Of Columbia, Maryland Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,995, issued on July 15, was assigned to Arcellx Inc. (Redwood City, Calif.) and Subdomain LLC (Redwood City, Calif.).

"De novo binding domain containing polypeptides and uses thereof" was invented by David William Lafleur (Washington) and David M. Hilbert (Gaithersburg, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are de novo binding domain containing polypeptides (DBDpp) that specifically bind a target of interest. Nucleic acids encoding the DBDpp, and vectors and host cells containing the nucleic acids are also provided. Libraries of DBDpp, methods of producing and screening such libraries and the DBDpp identified from such l...