ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,383, issued on July 8, was assigned to ARBUTUS BIOPHARMA Corp. (Vancouver, Canada).
"Cationic lipids containing silicon" was invented by Michael J. Abrams (Custer, Wash.), James Heyes (Vancouver, Canada), Richard J. Holland (Vancouver, Canada), Kieu Mong Lam (Richmond, Canada) and Mark Wood (Port Moody, Canada).
According to the abstract* released by the U.S. Patent & Trademark Office: "Certain embodiments of the invention provide a cationic lipid of formula (I): wherein R1, R2, R3 and R4 are defined as described herein, as well as methods of making these lipids. Certain embodiments of the invention also provide nucleic acid-lipid particles comprising a cationic lipid of formula (...