ALEXANDRIA, Va., July 16 -- United States Patent no. 12,357,705, issued on July 15, was assigned to ARBUTUS BIOPHARMA Corp. (Vancouver, Canada).
"Negatively charged peg-lipid conjugates" was invented by James Heyes (Vancouver, Canada), Kieu Mong Lam (Richmond, Canada) and Mark Wood (Port Moody, Canada).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides PEG-conjugated lipids of formula (I): A-B-C (I) wherein A, B, and C have any of the values defined in the specification, as well as compositions comprising the PEG-conjugated lipids of formula (I), nucleic acid lipid nanoparticles comprising the PEG-conjugated lipids of formula (I), and methods of using the PEG-conjugated lipids of formula (I...