ALEXANDRIA, Va., Aug. 12 -- United States Patent no. RE50,527, issued on Aug. 12, was assigned to Araxes Pharma LLC (San Diego).
"Covalent inhibitors of KRAS G12C" was invented by Pingda Ren (San Diego), Yi Liu (San Diego), Liansheng Li (San Diego), Jun Feng (San Diego) and Tao Wu (Carlsbad, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Irreversible inhibitors of G12C mutant K-Ras protein are provided. Also disclosed are methods to modulate the activity of G12C mutant K-Ras protein and methods of treatment of disorders mediated by G12C mutant K-Ras protein."
The patent was filed on Feb. 14, 2023, under Application No. 18/109,726.
*For further information, including images, charts and tables, please...