ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,625, issued on April 29, was assigned to APTAMIR THERAPEUTICS INC. (Naples, Fla.).
"Inhibition of mir-22 miRNA by APT-110" was invented by Marc Thibonnier (Naples, Fla.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Increase of energy expenditure as an effective treatment of obesity and related disorders is a target for drug research and development. A 15% increase of energy expenditure is believed to be sufficient to achieve significant weight and fat mass reduction while providing meaningful improvement of metabolic parameters. Disclosed herein is a method for pharmacological inhibition of miR-22-3p, which represents a new therapeutic approach for ...