ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,231, issued on Aug. 5, was assigned to APOGEE PHARMACEUTICALS INC. (Burnaby, Canada).
"Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof" was invented by Safwat Mohamed Rabea (Richmond, Canada), David Earl Bogucki (Surrey, Canada) and Kaiji Hu (Burnaby, Canada).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compounds of Formula I that are useful as Monoacylglycerol lipase (MAGL) inhibitorsThese compounds may be used in pharmaceutical compositions, formulations, and methods for the treatment of disease states, disorders, and conditions benefited by the inhibition or modulation of MAGL activity, suc...