US Patent Issued to AP Biosciences on May 27 for "Bispecific CD137-binding antibodies for T-cell activation" (Taiwanese, American Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,409, issued on May 27, was assigned to AP Biosciences Inc. (Taipei, Taiwan).

"Bispecific CD137-binding antibodies for T-cell activation" was invented by Jhong-Jhe You (Taipei, Taiwan), Ching-Hsuan Hsu (Taoyaun, Taiwan), Po-Lin Huang (Taipei, Taiwan) and Jeng-Horng Her (San Jose, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Antibodies that include an antigen binding region that binds to CD137 are provided herein. Also provided herein are bispecific antibodies that include a first antigen binding region that binds to CD137 and a second antigen binding region that binds to an immune checkpoint molecule, an immune stimulatory molecule, or a tum...